Detalhe da pesquisa
1.
Human lung cancer harbors spatially organized stem-immunity hubs associated with response to immunotherapy.
Nat Immunol
; 25(4): 644-658, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38503922
2.
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.
Cell
; 184(26): 6262-6280.e26, 2021 12 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34910928
3.
Spatially organized multicellular immune hubs in human colorectal cancer.
Cell
; 184(18): 4734-4752.e20, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34450029
4.
Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer.
Cell
; 182(6): 1474-1489.e23, 2020 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32841603
5.
Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics.
Cell
; 176(6): 1325-1339.e22, 2019 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30827679
6.
Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.
Cell
; 175(4): 998-1013.e20, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30388456
7.
Heavy Metal Enlightens Tumor Immunity.
Cell
; 169(4): 567-569, 2017 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28475889
8.
Targeted pseudouridylation: An approach for suppressing nonsense mutations in disease genes.
Mol Cell
; 83(4): 637-651.e9, 2023 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36764303
9.
Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma.
Cell
; 176(1-2): 404, 2019 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30633907
10.
Mega-scale experimental analysis of protein folding stability in biology and design.
Nature
; 620(7973): 434-444, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37468638
11.
Targeting TBK1 to overcome resistance to cancer immunotherapy.
Nature
; 615(7950): 158-167, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36634707
12.
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets.
Nature
; 595(7865): 107-113, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33915569
13.
Viral afterlife: SARS-CoV-2 as a reservoir of immunomimetic peptides that reassemble into proinflammatory supramolecular complexes.
Proc Natl Acad Sci U S A
; 121(6): e2300644120, 2024 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38306481
14.
NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts.
Blood
; 141(13): 1584-1596, 2023 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36375120
15.
CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis.
Blood
; 141(20): 2508-2519, 2023 05 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36800567
16.
Pseudouridylation-mediated gene expression modulation.
Biochem J
; 481(1): 1-16, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38174858
17.
Broadcasting of amplitude- and frequency-modulated c-di-GMP signals facilitates cooperative surface commitment in bacterial lineages.
Proc Natl Acad Sci U S A
; 119(4)2022 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35064082
18.
Single-cell atlas of the liver myeloid compartment before and after cure of chronic viral hepatitis.
J Hepatol
; 80(2): 251-267, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36972796
19.
Policy Interventions to Enhance Medical Care for People With Obesity in the United States-Challenges, Opportunities, and Future Directions.
Milbank Q
; 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38332667
20.
The Problem of Pain in Rheumatology: Variations in Case Definitions Derived From Chronic Pain Phenotyping Algorithms Using Electronic Health Records.
J Rheumatol
; 51(3): 297-304, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38101917